Oxidation Induced Changes in Lipid Mobility in Lipoproteins Followed by Steady State Fluorescence Anisotropy
نویسندگان
چکیده
The oxidation induced changes in the lipid layer of the lipoprotein particles of LDL and HDLs have been followed by measuring the steady-state polarization anisotropy of the fluorescence probe TMA-DPH incorporated in the lipid layer. The mobility restriction gradually increases with oxidation in LDL and HDL2 indicating the oxidation-induced structuring of lipids, while the effect of oxidation in HDL3 is negligible.
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